靶向細(xì)胞因子或其受體的中和抗體是研究免疫調(diào)節(jié)和開發(fā)治療策略的有力工具。InvivoGen提供多種高品質(zhì)重組單克隆抗體(monoclonal antibody, mAb)，這些抗體源自引證詳實(shí)的生物仿制藥或自主研發(fā)的克隆產(chǎn)品。我們提供來源于人類或小鼠的細(xì)胞因子靶向和細(xì)胞因子受體靶向mAb。為保證最-佳性能，每個(gè)批次均使用對(duì)應(yīng)的報(bào)告細(xì)胞和重組細(xì)胞因子進(jìn)行功能測(cè)試和驗(yàn)證。

主要特點(diǎn)

• 重組單克隆抗體

• 源自引證詳實(shí)的生物仿制藥或自主研發(fā)的

• 產(chǎn)自CHO細(xì)胞

• 經(jīng)過驗(yàn)證的中和作用

• 驗(yàn)證無內(nèi)毒素

• 提供InvivoFit^TM級(jí)別，可用于小鼠體內(nèi)研究

如需購(gòu)買Invivogen公司產(chǎn)品，請(qǐng)聯(lián)系Invivogen授權(quán)代理商欣博盛生物

應(yīng) 用

• 中和試驗(yàn)

• 檢測(cè)和生物活性試驗(yàn)

• 篩選試驗(yàn)

	InvivoGen中和抗體有哪些形式？
生物仿制藥mAb 重組mAb，其特征是候選藥物或治療藥物的可變區(qū)和恒定區(qū)。 修飾同型的生物仿制藥mAb 對(duì)原始同型進(jìn)行了修飾的重組生物仿制藥mAb。		自主研發(fā)的mAb 產(chǎn)自InvivoGen特-有的雜交瘤的重組mAb。在沒有可用的生物仿制藥的情況下開發(fā)。 InvivoFitTM mAbs 具有鼠源可變區(qū)和恒定區(qū)的高質(zhì)量重組mAb，專門針對(duì)小鼠體內(nèi)研究。

產(chǎn)品	靶點(diǎn)物種	克隆	同型	貨號(hào)
細(xì)胞因子抗體
Anti-hAPRIL-hIgG2	Human	Sibeprenlimab biosimilar - CAS # 2382896-07-1	Human IgG2	hapril-mab2
Anti-hBAFF-hIgG1	Human	Belimumab biosimilar - CAS # 356547-88-1	Human IgG1	hbaff-mab1
Anti-hCD40L-hIgG1	Human	Frexalimab biosimilar - CAS #2515463-86-0	Human IgG1	h40l-mab1
Anti-hIFN-α-hIgG1	Human	Rontalizumab biosimilar - CAS #948570-30-7	Human IgG1	hifna-mab1
Anti-hIFN-β-IgG	Human	Clone 10B10	Mouse IgG2a	mabg2-hifnb-3
Anti-hIFN-γ-hIgG1	Human	Fontolizumab biosimilar - CAS #326859-36-3	Human IgG1	hifng-mab1
Anti-hIL-1α-IgG1	Human	Clone 7D4	Human IgG1	mabg-hil1a-3
Anti-mIL-1α-mIgG1	Mouse	Clone 6H7	Mouse IgG1	mil1a-mab9-02
Anti-hIL-1β-IgG1	Human	Clone 4H5	Mouse IgG1	mabg-hil1b-3
Anti-mIL-1β-mIgG1	Mouse	Clone 7E3	Mouse IgG1	mil1b-mab9-02
Anti-mIL-2-mIgG1e3	Mouse	Clone S4B6	Mouse IgG1e3 (D265A)	mil2-mab15-02
Anti-hIL-6-IgG	Human	Clone 3H3	Mouse IgG1	mabg-hil6-3
Anti-mIL-6-mIgG1e3	Mouse	Clone 10F9	Mouse IgG1e3 (D265A)	mil6-mab15-02
Anti-hIL-9-hIgG1	Human	Enokizumab biosimilar - CAS #909875-08-7	Human IgG1	hil9-mab1
Anti-hIL-10-hIgG1	Human	Clone 20G2	Human IgG1	mab1-hil10
Anti-hIL-12/IL-23-p40-hIgG1	Human	Ustekinumab biosimilar - CAS #815610-63-0	Human IgG1	hil12p40-mab1
Anti-mIL-13-mIgG1	Mouse	Clone 8H8	Mouse IgG1	mil13-mab9-02
Anti-hIL-15-hIgG1	Human	Ordesekimab biosimilar - CAS #879293-15-9	Human IgG1	hil15-mab1
Anti-hIL-16-hIgG1	Human	Clone 14.1	Human IgG1	hil16-mab1-02
Anti-mIL-16-mIgG1e3	Mouse	Clone 14.1	Mouse IgG1e3 (D265A)	mil16-mab15-02
Anti-hIL17A-hIgG1	Human	Secukinumab biosimilar - CAS #1229022-83-6	Human IgG1	hil17a-mab1
Anti-hIL-18-hIgG1-FES	Human	Camoteskimab biosimilar - CAS #2492472-82-7	Human IgG1 (L242F/L243E/P339S)	hil18-mab16
Anti-hIL-20-hIgG4 (S228P)	Human	Fletikumab biosimilar - CAS #1357158-22-5	Human IgG4 (S228P)	hil20-mab14
Anti-hIL-21-hIgG1	Human	Avizakimab biosimilar - CAS #2229685-51-0	Human IgG1 (M252Y/S254T/T256E)	hil21-mab1
Anti-hIL-22-hIgG1	Human	Fezakinumab biosimilar - CAS #1007106-86-6	Human IgG1	hil22-mab1
Anti-hIL-25-hIgG1	Human	Clone 15G10	Human IgG1	hil25-mab1
Anti-hIL-28a-IgG	Human	Clone 21C3	Mouse IgG1	mabg-hil28a-3
Anti-hIL-28b-IgG	Human	Clone 18F4	Mouse IgG1	mabg-hil28b-3
Anti-mIL-28b-mIgG1	Mouse	Clone 3C11	Mouse IgG1	mil28b-mab9-02
Anti-hIL-29-mIgG1	Human	Clone 6A11	Mouse IgG1	mab9-hil29
Anti-hRANKL-hIgG2	Human	Denosumab biosimilar - CAS #615258-40-7	Human IgG2 (*)	hrankl-mab2
Anti-hTGF-β-hIgG4 (S228P)	Human	Fresolimumab biosimilar - CAS #948564-73-6	Human IgG4 (S228P)	htgfb-mab14
Anti-hTL1A-hIgG1	Human	Tulisokibart biosimilar - CAS #2648504-55-4	Human IgG1	htl1a-mab1
Anti-hTNF-α-hIgG1	Human	Adalimumab biosimilar - CAS #331731-18-1	Human IgG1 (*)	htnfa-mab1
Anti-hTSLP-hIgG2	Human	Tezepelumab biosimilar - CAS #1572943-04-4	Human IgG2	htslp-mab2
細(xì)胞因子受體抗體
Anti-hEGFR-hIgG1	Human	Cetuximab biosimilar - CAS #205923-56-4	Human IgG1	hegfr-mab1
Anti-hGM-CSFR-hIgG4 (S228P)	Human	Mavrilimumab biosimilar - CAS #1085337-57-0	Human IgG4 (S228P)	hgmcsfr-mab14
Anti-hIFNAR-hIgG1-FES	Human	Anifrolumab biosimilar - CAS #1326232-46-5	Human IgG1 (L242F/L243E/P339S) (*)	hifnar-mab16
Anti-hIL1RAP-hIgG1	Human	Nidanilimab biosimilar - CAS #2171061-85-9	Human IgG1	hil1rap-mab1
Anti-hIL-3R-hIgG1-DE	Human	Talacotuzumab biosimilar - CAS #1826831-79-1	Human IgG1 (S239D/I332E)	hil3r-mab18
Anti-hIL-5R-hIgG1fut	Human	Benralizumab biosimilar - CAS #1044511-01-4	Human IgG1	hil5r-mab13
Anti-hIL6R-To-hIgG1	Human	Tocilizumab biosimilar - CAS #375823-41-9	Human IgG1(*)	hil6rto-mab1
Anti-hIL-31R-hIgG2	Human	Nemolizumab biosimilar - CAS #1476039-58-3	Human IgG2	hil31r-mab2
Anti-hIL-33R-hIgG2	Human	Astegolimab biosimilar - CAS #2173054-79-8	Human IgG2	hil33r-mab2
Anti-hIL-36R-hIgG4 (S228P)	Human	Imsidolimab biosimilar - CAS #2102543-86-0	Human IgG4 (S228P)	hil36r-mab14

INVIVOFIT^TM GRADE

InvivoFit™是專為體內(nèi)研究設(shè)計(jì)的高質(zhì)量標(biāo)準(zhǔn)。InvivoFit™產(chǎn)品經(jīng)0.2μm過濾除菌，并在嚴(yán)格的無菌條件下罐裝。各批次產(chǎn)品的細(xì)菌污染物(內(nèi)毒素和脂蛋白)水平均通過瘊試劑盒(LAL)檢測(cè)以及TLR2和TLR4報(bào)告細(xì)胞檢測(cè)進(jìn)行驗(yàn)證。

(*) 多種同型可供選擇，詳情請(qǐng)聯(lián)系我們的代理商欣博盛生物，或訪問我們的網(wǎng)站。

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